Everyone involved in investing knows that there are no guarantees for profits!

So, to answer directly to the second part of your question, are there any chances for you to lose money while investing? Well, definitely yes.

However, when this is done by professionals like the guys from ISEC WM, the chances are slim. The trick for doing so is that the portfolio you will get with this company is constantly monitored, and if something needs to be adjusted, it is done on time. This is also called risk management. The same is true for the first part of your question.

There are rules on what assets you need to invest in when there is economic turmoil, what should be the ratio between the instruments in one portfolio, and many more tricks. When there is economic turmoil, it provides opportunities as well. So with good diversification, this is not something that you should worry about.

No, your investments can't be devalued if you work with the ISEC WM. It's plain as a day these guys are experts at rebalancing the portfolio, redistributing funds depending on the current situation in the market.
If there are any upheavals that can potentially devalue your investments, they just do everything to decrease the percentage of high risk assets in the portfolio substituting them with such low risk ones as bonds or fixed income securities. And they do it constantly, like every day, and you can even track all their actions in the personal area.