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on 9/27/18The FDA has stated that Benzoyl Peroxide, the main Proactive ingredient, is generally safe for use (GRASE) They also follow all of the FDA rules and regulations regarding over the counter products.
I don't feel like the ingredients in Proactiv are safe. Benzoyl Peroxide is really harsh and you don't really want to be killing all the bacteria on your skin. Some of the bacteria is good and you actually need it!